ADB-FUBINACA

300.002,600.00

Minimum Order: 50g
Purity: ≥98%
CAS Number: 1445583-51-6
Formula: C21H23FN4O2
Molar mass: 382.43 g/mol g·mol−1

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Description

ADB-FUBINACA

ADB-FUBINACA is a designer drug identified in synthetic cannabis blends in Japan in 2013.[1] The (S) enantiomer of ADB-FUBINACA is claimed in Pfizer patent WO 2009/106982 and has been reported to be a potent agonist of the CB1 receptor and CB2 receptor with an EC50 value of 1.2 nM and 3.5 nM respectively. ADB-FUBINACA features a carboxamide group at the 3-indazole position, like SDB-001 and STS-135. ADB-FUBINACA appears to be the product of rational drug design, since it differs from AB-FUBINACA only by the replacement of the isopropyl group with a tert-butyl group.

Metabolism

Twenty-three ADB-FUBINACA major metabolites were identified in several incubations with cryopreserved human hepatocytes. Major metabolic pathways were alkyl and indazole hydroxylation, terminal amide hydrolysis, subsequent glucuronide conjugations, and dehydrogenation.

Synthetic cannabinoids

Synthetic cannabinoids are a class of molecules that bind to the same receptors to which cannabinoids in cannabis plants THC and CBD attach. They are designer drugs, commonly sprayed onto plant matter and are usually smoked, although they have also been ingested as a concentrated liquid form in the US and UK. They have been marketed as herbal incense, or “herbal smoking blends”, and sold under common names like K2, Spice, and Synthetic Marijuana. They are often labeled “not for human consumption” for liability defense. A large and complex variety of synthetic cannabinoids are designed in an attempt to avoid legal restrictions on cannabis, making synthetic cannabinoids designer drugs.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this drugs only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Additional information

Quantity

50g, 100g, 250g, 500g, 1kg or more (Negotiable)

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